Characterization of a new selective glucocorticoid receptor modulator with anorexigenic activity

Abstract Obesity, a worldwide epidemic, leads to various metabolic disorders threatening human health. In response to stress or fasting, glucocorticoid (GC) levels are elevated to promote food intake. This involves GC-induced expression of the orexigenic neuropeptides in agouti-related protein (AgRP...

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Bibliographic Details
Main Authors: Junekyoung Lee, Yeonghun Song, Young A. Kim, Intae Kim, Jooseon Cha, Su Won Lee, Yoonae Ko, Chong-Su Kim, Sanghee Kim, Seunghee Lee
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-58546-1