Neuropathogenicity of Two Saffold Virus Type 3 Isolates in Mouse Models.

Saffold virus (SAFV), a picornavirus, is occasionally detected in children with acute flaccid paralysis, meningitis, and cerebellitis; however, the neuropathogenicity of SAFV remains undetermined.The virulence of two clinical isolates of SAFV type 3 (SAFV-3) obtained from a patient with aseptic meni...

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Main Authors: Osamu Kotani, Asif Naeem, Tadaki Suzuki, Naoko Iwata-Yoshikawa, Yuko Sato, Noriko Nakajima, Takushi Hosomi, Hiroyuki Tsukagoshi, Kunihisa Kozawa, Hideki Hasegawa, Fumihiro Taguchi, Hiroyuki Shimizu, Noriyo Nagata
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4734772?pdf=render