Role of extracellular microRNA-146a-5p in host innate immunity and bacterial sepsis

Summary: Extracellular miRNAs (ex-miRNAs) mediate intercellular communication and play a role in diverse physiological and pathological processes. Using small RNA sequencing, we identify that miRNAs are the most abundant RNA species in the plasma and differentially expressed in murine and human seps...

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Main Authors: Sheng Wang, Yang Yang, Andrew Suen, Jing Zhu, Brittney Williams, Jiang Hu, Fengqian Chen, Rosemary Kozar, Shiqian Shen, Ziyi Li, Anjana Jeyaram, Steven M. Jay, Lin Zou, Wei Chao
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:iScience
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Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221014127