Hepatocyte-specific Prominin-1 protects against liver injury-induced fibrosis by stabilizing SMAD7

Hepatocyte-specific Prominin-1 protects against liver injury-induced fibrosis by stabilizing SMAD7

Liver disease: Preventing progression of fibrosis Progression of liver fibrosis is kept in check by a regulatory protein that switches off a signaling pathway responsible for cell death and subsequent scar tissue formation. Liver fibrosis is a common outcome of alcoholism, viral infection, and hepat...

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Bibliographic Details
Main Authors: Hyun Lee, Dong-Min Yu, Myeong-Suk Bahn, Young-Jae Kwon, Min Jee Um, Seo Yeon Yoon, Ki-Tae Kim, Myoung-Woo Lee, Sung-Je Jo, Sungsoo Lee, Seung-Hoi Koo, Ki Hoon Jung, Jae-Seon Lee, Young-Gyu Ko
Format: Article
Language:English
Published: Nature Publishing Group 2022-08-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-022-00831-y

Internet

https://doi.org/10.1038/s12276-022-00831-y

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