Effects of partner proteins on BCA2 RING ligase activity

<p>Abstract</p> <p>Background</p> <p>BCA2 is an E3 ligase linked with hormone responsive breast cancers. We have demonstrated previously that the RING E3 ligase BCA2 has autoubiquitination activity and is a very unstable protein. Previously, only Rab7, tetherin, ubiquit...

Full description

Bibliographic Details
Main Authors: Bacopulos Stephanie, Amemiya Yutaka, Yang Wenyi, Zubovits Judit, Burger Angelika, Yaffe Martin, Seth Arun K
Format: Article
Language:English
Published: BMC 2012-02-01
Series:BMC Cancer
Online Access:http://www.biomedcentral.com/1471-2407/12/63