Simulation of the crosstalk between glucose and acetaminophen metabolism in a liver zonation model
The liver metabolizes a variety of substances that sometimes interact and regulate each other. The modeling of a single cell or a single metabolic pathway does not represent the complexity of the organ, including metabolic zonation (heterogeneity of functions) along with liver sinusoids. Here, we in...
Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | English |
Publicado: |
Frontiers Media S.A.
2022-09-01
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Series: | Frontiers in Pharmacology |
Subjects: | |
Acceso en liña: | https://www.frontiersin.org/articles/10.3389/fphar.2022.995597/full |