ECL 3.0: a sensitive peptide identification tool for cross-linking mass spectrometry data analysis

Abstract Background Cross-linking mass spectrometry (XL-MS) is a powerful technique for detecting protein–protein interactions (PPIs) and modeling protein structures in a high-throughput manner. In XL-MS experiments, proteins are cross-linked by a chemical reagent (namely cross-linker), fragmented,...

Full description

Bibliographic Details
Main Authors: Chen Zhou, Shuaijian Dai, Shengzhi Lai, Yuanqiao Lin, Xuechen Zhang, Ning Li, Weichuan Yu
Format: Article
Language:English
Published: BMC 2023-09-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-023-05473-z