RAGE and its ligand amyloid beta promote retinal ganglion cell loss following ischemia-reperfusion injury

RAGE and its ligand amyloid beta promote retinal ganglion cell loss following ischemia-reperfusion injury

IntroductionGlaucoma is a progressive neurodegenerative disease associated with age. Accumulation of amyloid-beta (Aß) proteins in the ganglion cell layer (GCL) and subsequent retinal ganglion cell (RGC) loss is an established pathological hallmark of the disease. The mechanism through which Aß prov...

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Bibliographic Details
Main Authors: Nafiseh Seyed Hosseini Fin, Dana Georgevsky, Maria B. Sukkar, S. Mojtaba Golzan
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Cellular Neuroscience
Subjects:
receptor for advanced glycation end products
amyloid beta
retinal ischemia-reperfusion
retinal ganglion cell loss
glaucoma
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2023.1156084/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2023.1156084/full

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