Activated peripheral lymphocytes with increased expression of cell adhesion molecules and cytotoxic markers are associated with dengue fever disease

The immune mechanisms involved in dengue fever and dengue hemorrhagic/dengue shock syndrome are not well understood. The ex vivo activation status of immune cells during the dengue disease in patients was examined. CD4and CD8 T cells were reduced during the acute phase. Interestingly, CD8 T cells co...

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Bibliographic Details
Main Authors: Elzinandes L Azeredo, Sonia MO Zagne, Allan R Alvarenga, Rita MR Nogueira, Claire F Kubelka, Luzia M de Oliveira-Pinto
Format: Article
Language:English
Published: Fundação Oswaldo Cruz (FIOCRUZ) 2006-06-01
Series:Memorias do Instituto Oswaldo Cruz
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762006000400016