Sertoli Cell Immune Regulation: A Double-Edged Sword

The testis must create and maintain an immune privileged environment to protect maturing germ cells from autoimmune destruction. The establishment of this protective environment is due, at least in part, to Sertoli cells. Sertoli cells line the seminiferous tubules and form the blood-testis barrier...

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Bibliographic Details
Main Authors: Rachel L. Washburn, Taylor Hibler, Gurvinder Kaur, Jannette M. Dufour
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Immunology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.913502/full