GPR183 Is Dispensable for B1 Cell Accumulation and Function, but Affects B2 Cell Abundance, in the Omentum and Peritoneal Cavity

GPR183 Is Dispensable for B1 Cell Accumulation and Function, but Affects B2 Cell Abundance, in the Omentum and Peritoneal Cavity

B1 cells constitute a specialized subset of B cells, best characterized in mice, which is abundant in body cavities, including the peritoneal cavity. Through natural and antigen-induced antibody production, B1 cells participate in the early defense against bacteria. The G protein-coupled receptor 18...

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Bibliographic Details
Main Authors: Line Barington, Liv von Voss Christensen, Kristian Kåber Pedersen, Kristine Niss Arfelt, Martin Roumain, Kristian Høj Reveles Jensen, Viktoria Madeline Skovgaard Kjær, Viktorija Daugvilaite, John F. Kearney, Jan Pravsgaard Christensen, Gertrud Malene Hjortø, Giulio G. Muccioli, Peter Johannes Holst, Mette Marie Rosenkilde
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Cells
Subjects:
GPCR
7TM receptor
GPR183
EBI2
B1 cell
B-1 cell
Online Access:https://www.mdpi.com/2073-4409/11/3/494

Internet

https://www.mdpi.com/2073-4409/11/3/494

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