A 2-Gene Host Signature for Improved Accuracy of COVID-19 Diagnosis Agnostic to Viral Variants

A 2-Gene Host Signature for Improved Accuracy of COVID-19 Diagnosis Agnostic to Viral Variants

ABSTRACT The continued emergence of SARS-CoV-2 variants is one of several factors that may cause false-negative viral PCR test results. Such tests are also susceptible to false-positive results due to trace contamination from high viral titer samples. Host immune response markers provide an orthogon...

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Bibliographic Details
Main Authors: Jack Albright, Eran Mick, Estella Sanchez-Guerrero, Jack Kamm, Anthea Mitchell, Angela M. Detweiler, Norma Neff, Alexandra Tsitsiklis, Paula Hayakawa Serpa, Kalani Ratnasiri, Diane Havlir, Amy Kistler, Joseph L. DeRisi, Angela Oliveira Pisco, Charles R. Langelier
Format: Article
Language:English
Published: American Society for Microbiology 2023-02-01
Series:mSystems
Subjects:
COVID-19
diagnostics
classifier
gene expression
metagenomics
transcriptomics
Online Access:https://journals.asm.org/doi/10.1128/msystems.00671-22

Internet

https://journals.asm.org/doi/10.1128/msystems.00671-22

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