Species specific morphological alterations in liver tissue after biliary occlusion in rat and mouse: Similar but different.

<h4>Background</h4>The selection of the appropriate species is one of the key issues in experimental medicine. Bile duct ligation is the mostly used experimental model in rodents to explore special aspects of occlusive cholestasis. We aimed to clarify if rats or mice are suitable for the...

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Bibliographic Details
Main Authors: Beate Richter, Constanze Sänger, Franziska Mussbach, Hubert Scheuerlein, Utz Settmacher, Uta Dahmen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0271975