PEG-modified carbon-based nanoparticles as tumor-targeted drug delivery system reducing doxorubicin-induced cardiotoxicity

PEG-modified carbon-based nanoparticles as tumor-targeted drug delivery system reducing doxorubicin-induced cardiotoxicity

Herein, a doxorubicin-loaded carbon-based drug delivery system, denoted as PC-DOX, composed of pH-responsive imine bond was developed for the tumor-targeted treatment. PC-DOX with a uniform particle size around 180 nm was synthesized by coating of as-synthesized hollow carbon-based nanoparticles (NP...

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Bibliographic Details
Main Authors: Lide Wang, Xiufeng Xu, Lichao Chu, Chun Meng, Longwu Xu, Yuying Wang, Qiuhong Jiao, Tao Huang, Yudan Zhao, Xiaohong Liu, Jingtian Li, Baolong Zhou, Tao Wang
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Biomedicine & Pharmacotherapy
Subjects:
DOX
Drug delivery
Anti-tumor
Cardiotoxicity
Cardioprotection
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223016347

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http://www.sciencedirect.com/science/article/pii/S0753332223016347

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