CXCR7 participates in CXCL12-mediated migration and homing of leukemic and normal hematopoietic cells
Abstract CXCR4 was the first receptor identified for CXCL12, but a second receptor, CXCR7, has also been described and its function in hematopoietic cells remains unknown. By inhibition of CXCR4 and/or CXCR7, we showed that CXCR7 participates in normal CD34+ and U937 cell migration and prevents down...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2018-02-01
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Series: | Stem Cell Research & Therapy |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13287-017-0765-1 |