Peripheral blood transcriptome profiling enables monitoring disease progression in dystrophic mice and patients

Peripheral blood transcriptome profiling enables monitoring disease progression in dystrophic mice and patients

Abstract DMD is a rare disorder characterized by progressive muscle degeneration and premature death. Therapy development is delayed by difficulties to monitor efficacy non‐invasively in clinical trials. In this study, we used RNA‐sequencing to describe the pathophysiological changes in skeletal mus...

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Detaylı Bibliyografya
Asıl Yazarlar: Mirko Signorelli, Mitra Ebrahimpoor, Olga Veth, Kristina Hettne, Nisha Verwey, Raquel García‐Rodríguez, Christa L Tanganyika‐deWinter, Luz B Lopez Hernandez, Rosa Escobar Cedillo, Benjamín Gómez Díaz, Olafur T Magnusson, Hailiang Mei, Roula Tsonaka, Annemieke Aartsma‐Rus, Pietro Spitali
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: Springer Nature 2021-03-01
Seri Bilgileri:EMBO Molecular Medicine
Konular:
biomarkers
Duchenne muscular dystrophy
dystrophinopathies
RNA‐seq
Online Erişim:https://doi.org/10.15252/emmm.202013328

Internet

https://doi.org/10.15252/emmm.202013328

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