Unraveling Heterogeneity in the Aging Hematopoietic Stem Cell Compartment: An Insight From Single-cell Approaches

Unraveling Heterogeneity in the Aging Hematopoietic Stem Cell Compartment: An Insight From Single-cell Approaches

Specific cell types and, therefore, organs respond differently during aging. This is also true for the hematopoietic system, where it has been demonstrated that hematopoietic stem cells alter a variety of features, such as their metabolism, and accumulate DNA damage, which can lead to clonal outgrow...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy:	Fei Yang, Craig Nourse, G. Vignir Helgason, Kristina Kirschner
Format:	Artykuł
Język:	English
Wydane:	Wiley 2023-06-01
Seria:	HemaSphere
Dostęp online:	http://journals.lww.com/10.1097/HS9.0000000000000895

Podobne zapisy

The Ins and Outs of Autophagy and Metabolism in Hematopoietic and Leukemic Stem Cells: Food for Thought
od: Angela Ianniciello, i wsp.
Wydane: (2018-09-01)

Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment
od: Kristina Kirschner, i wsp.
Wydane: (2017-05-01)

Competition between hematopoietic stem and progenitor cells controls hematopoietic stem cell compartment size
od: Runfeng Miao, i wsp.
Wydane: (2022-08-01)

Clonal dominance and transplantation dynamics in hematopoietic stem cell compartments.
od: Peter Ashcroft, i wsp.
Wydane: (2017-10-01)

Resetting the T Cell Compartment in Autoimmune Diseases With Autologous Hematopoietic Stem Cell Transplantation: An Update
od: Lisanne Lutter, i wsp.
Wydane: (2018-04-01)

Heterogeneous Responses of Hematopoietic Stem Cells to Inflammatory Stimuli Are Altered with Age
od: Mann, Mati, i wsp.
Wydane: (2019)

Heterogeneous Responses of Hematopoietic Stem Cells to Inflammatory Stimuli Are Altered with Age
od: Mati Mann, i wsp.
Wydane: (2018-12-01)

Emerging heterogeneous compartments by viruses in single bacterial cells
od: Jimmy T. Trinh, i wsp.
Wydane: (2020-07-01)

Hematopoietic stem cells in co-culture with mesenchymal stromal cells - modeling the niche compartments in vitro
od: Duohui Jing, i wsp.
Wydane: (2010-04-01)

Hematopoietic stem cell heterogeneity and age-associated platelet bias are evolutionarily conserved
od: Aksöz, M, i wsp.
Wydane: (2024)

Unraveling immune cell heterogeneity in autoimmune arthritis: insights from single-cell RNA sequencing
od: Sotaro Nakajima, i wsp.
Wydane: (2024-10-01)

Combined Analysis of Endothelial, Hematopoietic, and Mesenchymal Stem Cell Compartments Shows Simultaneous but Independent Effects of Age and Heart Disease
od: Carine Ghem, i wsp.
Wydane: (2017-01-01)

Heterogeneity, Self-Renewal, and Differentiation of Hematopoietic Stem Cells
od: Roland Jurecic, i wsp.
Wydane: (2012-01-01)

Inflamm-aging of hematopoietic stem cells
od: Zhiyang Chen, i wsp.
Wydane: (2019-10-01)

Inflammation and hematopoietic stem cells aging
od: Hanqing He, i wsp.
Wydane: (2021-01-01)

Single-cell landscape analysis unravels molecular programming of the human B cell compartment in chronic GVHD
od: Jonathan C. Poe, i wsp.
Wydane: (2023-06-01)

The impact of ageing on the human haematopoietic stem cell and memory T cell compartments through the lens of single cell transcriptome analysis
od: Gafencu, GA
Wydane: (2022)

Prepatterning in the stem cell compartment.
od: Peter D Tonge, i wsp.
Wydane: (2010-05-01)

Emerging insights into epigenetics and hematopoietic stem cell trafficking in age-related hematological malignancies
od: Yang Xinyi, i wsp.
Wydane: (2024-11-01)

Understanding intrinsic hematopoietic stem cell aging
od: Eva Mejia-Ramirez, i wsp.
Wydane: (2020-01-01)

Microenvironmental contributions to hematopoietic stem cell aging
od: Ya-Hsuan Ho, i wsp.
Wydane: (2020-01-01)

Inflammation and Aging of Hematopoietic Stem Cells in Their Niche
od: Daozheng Yang, i wsp.
Wydane: (2021-07-01)

Unravelling B cell heterogeneity: insights into flow cytometry-gated B cells from single-cell multi-omics data
od: Pernes, JI, i wsp.
Wydane: (2024)

Unravelling B cell heterogeneity: insights into flow cytometry-gated B cells from single-cell multi-omics data
od: Jane I. Pernes, i wsp.
Wydane: (2024-04-01)

Spatially Annotated Single Cell Sequencing for Unraveling Intratumor Heterogeneity
od: Myrthe M. Smit, i wsp.
Wydane: (2022-02-01)

Unraveling the Heterogeneity and Ontogeny of Dendritic Cells Using Single-Cell RNA Sequencing
od: Binyao Chen, i wsp.
Wydane: (2021-09-01)

Auto-Commentary on: “Targeting mitochondrial oxidative phosphorylation eradicates therapy-resistant chronic myeloid leukemia stem cells”
od: Lucie de Beauchamp, i wsp.
Wydane: (2018-01-01)

Unraveling Hematotoxicity of α-Amanitin in Cultured Hematopoietic Cells
od: Willemien F. J. Hof, i wsp.
Wydane: (2024-01-01)

Single cell RNA sequencing reveals molecular and functional platelet bias of aged hematopoietic stem cells
od: Nerlov, C, i wsp.
Wydane: (2016)

Insights into the role of intestinal microbiota in hematopoietic stem-cell transplantation
od: Daniele Zama, i wsp.
Wydane: (2020-01-01)

Modelling stem cell ageing: a multi-compartment continuum approach
od: Yanli Wang, i wsp.
Wydane: (2020-03-01)

DNA Damage Response in Hematopoietic Stem Cell Ageing
od: Tangliang Li, i wsp.
Wydane: (2016-06-01)

Epigenetic age acceleration in hematopoietic stem cell transplantation
od: Margherita Ursi, i wsp.
Wydane: (2024-10-01)

Mechanisms and rejuvenation strategies for aged hematopoietic stem cells
od: Xia Li, i wsp.
Wydane: (2020-04-01)

Single-cell RNA-seq analysis reveals compartment-specific heterogeneity and plasticity of microglia
od: Junying Zheng, i wsp.
Wydane: (2021-03-01)

Hematopoietic stem cell heterogeneity and age-related platelet bias: implications for bone marrow transplantation and blood disorders
od: Yalu Chen, i wsp.
Wydane: (2024-12-01)

Self-renewal of single mouse hematopoietic stem cells is reduced by JAK2V617F without compromising progenitor cell expansion.
od: David G Kent, i wsp.
Wydane: (2013-01-01)

Unravelling Heterogeneity of Amplified Human Amniotic Fluid Stem Cells Sub-Populations
od: Francesca Casciaro, i wsp.
Wydane: (2021-01-01)

Single-cell RNA-seq reveals changes in cell cycle and differentiation programs upon aging of hematopoietic stem cells
od: Kowalczyk, Monika S., i wsp.
Wydane: (2016)

Single-cell RNA-seq reveals a concomitant delay in differentiation and cell cycle of aged hematopoietic stem cells
od: Léonard Hérault, i wsp.
Wydane: (2021-02-01)