Unraveling Heterogeneity in the Aging Hematopoietic Stem Cell Compartment: An Insight From Single-cell Approaches

Specific cell types and, therefore, organs respond differently during aging. This is also true for the hematopoietic system, where it has been demonstrated that hematopoietic stem cells alter a variety of features, such as their metabolism, and accumulate DNA damage, which can lead to clonal outgrow...

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Bibliographic Details
Main Authors: Fei Yang, Craig Nourse, G. Vignir Helgason, Kristina Kirschner
Format: Article
Language:English
Published: Wiley 2023-06-01
Series:HemaSphere
Online Access:http://journals.lww.com/10.1097/HS9.0000000000000895