Novel molecular mechanisms by which ginger extract reduces the inflammatory stress in TNFα – activated human endothelial cells; decrease of Ninjurin-1, TNFR1 and NADPH oxidase subunits expression

Novel molecular mechanisms by which ginger extract reduces the inflammatory stress in TNFα – activated human endothelial cells; decrease of Ninjurin-1, TNFR1 and NADPH oxidase subunits expression

Dysfunction of endothelial cells (EC) is important for atherosclerosis progression. The aim of this study was to evaluate the potential of ginger extract (GEx), 6-gingerol (6-G) and 6-shogaol (6-Sh) to reverse EC dysfunction and to investigate its mechanism of action, using cultured human EC incubat...

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Bibliographic Details
Main Authors: Laura Toma, Mina Raileanu, Mariana Deleanu, Camelia S. Stancu, Anca V. Sima
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Journal of Functional Foods
Subjects:
Endothelial dysfunction
Ginger extract
Ninjurin-1
TNFR1
NADPH oxidase
RAGE
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464618304274

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http://www.sciencedirect.com/science/article/pii/S1756464618304274

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