Over-expression of miR-217 regulates EZH2 to promote osteogenic differentiation of BM-MSCs in osteoporotic mouse models

Objective To explore the effect of microRNA-217 (miR-217) on the osteogenic differentiation of bone marrow mesenchymal stem cells (BM-MSCs) in osteoporosis (OP) mouse model and potential regulatory mechanism. Methods The mice were divided into OP group and sham operation (sham) group with 12 in each...

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Bibliographic Details
Main Author: RUAN Feng, LI He-wei, GONG Yan-lin, LIU Jia-li, LIU Ping
Format: Article
Language:zho
Published: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2022-09-01
Series:Jichu yixue yu linchuang
Subjects:
Online Access:http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/1001-6325-42-9-1406.pdf