Modeling activity and target-dependent developmental cell death of mouse retinal ganglion cells ex vivo.

Programmed cell death is widespread during the development of the central nervous system and serves multiple purposes including the establishment of neural connections. In the mouse retina a substantial reduction of retinal ganglion cells (RGCs) occurs during the first postnatal week, coinciding wit...

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Bibliographic Details
Main Authors: Sylvie Voyatzis, Aude Muzerelle, Patricia Gaspar, Xavier Nicol
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3281910?pdf=render