Regional High Iron in the Substantia Nigra Differentiates Parkinson’s Disease Patients From Healthy Controls

Background: Iron is important in the pathophysiology of Parkinson’s disease (PD) specifically related to degeneration of the substantia nigra (SN). Magnetic resonance imaging (MRI) can be used to measure brain iron in the entire structure but this approach is insensitive to regional changes in iron...

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Bibliographic Details
Main Authors: Kiarash Ghassaban, Naying He, Sean Kumar Sethi, Pei Huang, Shengdi Chen, Fuhua Yan, Ewart Mark Haacke
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2019.00106/full