Extracellular Signal-Regulated Kinases: One Pathway, Multiple Fates

Extracellular Signal-Regulated Kinases: One Pathway, Multiple Fates

This comprehensive review delves into the multifaceted aspects of ERK signaling and the intricate mechanisms underlying distinct cellular fates. ERK1 and ERK2 (ERK) govern proliferation, transformation, epithelial–mesenchymal transition, differentiation, senescence, or cell death, contingent upon ac...

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Bibliographic Details
Main Authors: Xavier Deschênes-Simard, Mohan Malleshaiah, Gerardo Ferbeyre
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Cancers
Subjects:
cell proliferation
cell fate
ERK
senescence
cell signaling
EMT
Online Access:https://www.mdpi.com/2072-6694/16/1/95

Internet

https://www.mdpi.com/2072-6694/16/1/95

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