Design, Synthesis and Evaluation of Hesperetin Derivatives as Potential Multifunctional Anti-Alzheimer Agents

In this study we designed and synthesized a series of new hesperetin derivatives on the basis of the structural characteristics of acetylcholinesterase (AChE) dual-site inhibitors. The activity of the novel derivatives was also evaluated. Results showed that the synthesized hesperetin derivatives di...

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Bibliographic Details
Main Authors: Bo Li, Ai-Ling Huang, Yi-Long Zhang, Zeng Li, Hai-Wen Ding, Cheng Huang, Xiao-Ming Meng, Jun Li
Format: Article
Language:English
Published: MDPI AG 2017-06-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/22/7/1067