Chromosome 11q13 amplification correlates with poor response and prognosis to PD-1 blockade in unresectable hepatocellular carcinoma

Chromosome 11q13 amplification correlates with poor response and prognosis to PD-1 blockade in unresectable hepatocellular carcinoma

Background & aimsLittle is known about molecular biomarkers that predict the response and prognosis in unresectable hepatocellular carcinoma (HCC) treated with programmed death (PD)-1 inhibitors.MethodsA total of 62 HCC patients who underwent next-generation sequencing were retrospectively i...

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Bibliographic Details
Main Authors: Kai Yan, Ding Zhang, Yanan Chen, Wenfeng Lu, Mengli Huang, Jinping Cai, Shiqing Chen, Ting Bei, Yuezong Bai, Jian Lv, Yong Fu, Haibin Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Immunology
Subjects:
hyperprogressive disease
hepatocellular carcinoma
programmed cell death protein-1
chromosome 11q13 amplification
next-generation sequencing
multiplex immunofluorescence
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1116057/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1116057/full

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