Protein post-translational modification by lysine succinylation: Biochemistry, biological implications, and therapeutic opportunities

Protein post-translational modification by lysine succinylation: Biochemistry, biological implications, and therapeutic opportunities

Lysine succinylation (Ksuc) is a novel protein post-translational modification (PTM) wherein a succinyl group modifies a lysine residue. Ksuc leads to significant chemical and structural changes to the modified protein. Recent studies have shown that Ksuc might play an important role in organism phy...

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Bibliographic Details
Main Authors: Guo Zhao, Junfeng Zhen, Xinyuan Liu, Jinshuai Guo, Duanduan Li, Jianping Xie, Longxiang Xie
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-07-01
Series:Genes and Diseases
Subjects:
Disease
Eukaryotes
Lysine succinylation
Physiology
Prokaryotes
Protein post-translational modification
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304222000836

Internet

http://www.sciencedirect.com/science/article/pii/S2352304222000836

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