Identification and quantification of phytoprostanes and phytofurans in Acacia cyanophylla Lindl. seeds
Phytoprostanes and phytofurans are derived from peroxidation of α-linolenic acid (ALA) the main polyunsaturated fatty acid (PUFA) found in higher plants. These compounds are considered as excellent biomarkers of oxidative degradation and have demonstrated a wide range of biological activities (e.g....
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| Format: | Article |
| Language: | English |
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Elsevier
2022-10-01
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| Series: | Food Chemistry Advances |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772753X2200065X |
| _version_ | 1811293917352558592 |
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| author | Marwa Mersni Bingqing Zhou Guillaume Reversat Islem Yangui Mohamed Larbi Khouja Alexandre Guy Camille Oger Jean-Marie Galano Thierry Durand Chokri Messaoud Claire Vigor |
| author_facet | Marwa Mersni Bingqing Zhou Guillaume Reversat Islem Yangui Mohamed Larbi Khouja Alexandre Guy Camille Oger Jean-Marie Galano Thierry Durand Chokri Messaoud Claire Vigor |
| author_sort | Marwa Mersni |
| collection | DOAJ |
| description | Phytoprostanes and phytofurans are derived from peroxidation of α-linolenic acid (ALA) the main polyunsaturated fatty acid (PUFA) found in higher plants. These compounds are considered as excellent biomarkers of oxidative degradation and have demonstrated a wide range of biological activities (e.g. protection of neuronal cells against stress, anti-inflammatory). In the present work, these new active oxylipins, were detected for the first time in Acacia cyanophylla seeds collected in Tunisia from 7 ecotypes, using LC-MS/MS technology. The main PhytoP found was ent-9-L1-PhytoP, ranged from 3.30 ng/g (N-OB ecotype) to 19.14 ng/g (B-ZO ecotype). Three PhytoFs were detected with significantly higher values than PhytoPs. Multivariate analyses indicated a significant differentiation between compounds attributed to variation in climatic factors. This first complete PhytoP and PhytoF profile shows that Acacia cyanophylla Lindl. seeds could be as a new source of bioactive compounds for therapeutic and pharmaceutical applications. |
| first_indexed | 2024-04-13T05:08:41Z |
| format | Article |
| id | doaj.art-ecfc9c01e83049d5aeeb89a5a6157053 |
| institution | Directory Open Access Journal |
| issn | 2772-753X |
| language | English |
| last_indexed | 2024-04-13T05:08:41Z |
| publishDate | 2022-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Food Chemistry Advances |
| spelling | doaj.art-ecfc9c01e83049d5aeeb89a5a61570532022-12-22T03:01:06ZengElsevierFood Chemistry Advances2772-753X2022-10-011100077Identification and quantification of phytoprostanes and phytofurans in Acacia cyanophylla Lindl. seedsMarwa Mersni0Bingqing Zhou1Guillaume Reversat2Islem Yangui3Mohamed Larbi Khouja4Alexandre Guy5Camille Oger6Jean-Marie Galano7Thierry Durand8Chokri Messaoud9Claire Vigor10University of Carthage, National Institute of Applied Sciences and Technology (INSAT), UR17ES22 Laboratory of nanobiotechnology and valorization of medicinal phytoresources, Centre Urbain Nord, BP 676, 1080, Tunis Cedex, Tunisia; Institut of Biomolecules Max Mousseron (IBMM), UMR 5247 CNRS, ENSCM, University of Montpellier, Faculty of Pharmacy, MAMMA (Montpellier Alliance for Metabolomics and metabolism Analysis), BIOCampus, Montpellier, FranceInstitut of Biomolecules Max Mousseron (IBMM), UMR 5247 CNRS, ENSCM, University of Montpellier, Faculty of Pharmacy, MAMMA (Montpellier Alliance for Metabolomics and metabolism Analysis), BIOCampus, Montpellier, FranceInstitut of Biomolecules Max Mousseron (IBMM), UMR 5247 CNRS, ENSCM, University of Montpellier, Faculty of Pharmacy, MAMMA (Montpellier Alliance for Metabolomics and metabolism Analysis), BIOCampus, Montpellier, FranceUniversity of Carthage, National Institute of Applied Sciences and Technology (INSAT), UR17ES22 Laboratory of nanobiotechnology and valorization of medicinal phytoresources, Centre Urbain Nord, BP 676, 1080, Tunis Cedex, TunisiaUniversity of Carthage, National Institute of Research in Rural Engineering, Waters and Forests, BP 10, Ariana, 2080, TunisiaInstitut of Biomolecules Max Mousseron (IBMM), UMR 5247 CNRS, ENSCM, University of Montpellier, Faculty of Pharmacy, MAMMA (Montpellier Alliance for Metabolomics and metabolism Analysis), BIOCampus, Montpellier, FranceInstitut of Biomolecules Max Mousseron (IBMM), UMR 5247 CNRS, ENSCM, University of Montpellier, Faculty of Pharmacy, MAMMA (Montpellier Alliance for Metabolomics and metabolism Analysis), BIOCampus, Montpellier, FranceInstitut of Biomolecules Max Mousseron (IBMM), UMR 5247 CNRS, ENSCM, University of Montpellier, Faculty of Pharmacy, MAMMA (Montpellier Alliance for Metabolomics and metabolism Analysis), BIOCampus, Montpellier, FranceInstitut of Biomolecules Max Mousseron (IBMM), UMR 5247 CNRS, ENSCM, University of Montpellier, Faculty of Pharmacy, MAMMA (Montpellier Alliance for Metabolomics and metabolism Analysis), BIOCampus, Montpellier, FranceUniversity of Carthage, National Institute of Applied Sciences and Technology (INSAT), UR17ES22 Laboratory of nanobiotechnology and valorization of medicinal phytoresources, Centre Urbain Nord, BP 676, 1080, Tunis Cedex, Tunisia; Corresponding author at: Pôle Chimie Balard Recherche Institut des Biomolécules Max Mousseron (IBMM), UMR 5247, Université de Montpellier, CNRS, ENSCM, France, 1919 route de Mende, 34293, MONTPELLIER, cedex 5Institut of Biomolecules Max Mousseron (IBMM), UMR 5247 CNRS, ENSCM, University of Montpellier, Faculty of Pharmacy, MAMMA (Montpellier Alliance for Metabolomics and metabolism Analysis), BIOCampus, Montpellier, France; Corresponding author at: Pôle Chimie Balard Recherche Institut des Biomolécules Max Mousseron (IBMM), UMR 5247, Université de Montpellier, CNRS, ENSCM, France, 1919 route de Mende, 34293, MONTPELLIER, cedex 5Phytoprostanes and phytofurans are derived from peroxidation of α-linolenic acid (ALA) the main polyunsaturated fatty acid (PUFA) found in higher plants. These compounds are considered as excellent biomarkers of oxidative degradation and have demonstrated a wide range of biological activities (e.g. protection of neuronal cells against stress, anti-inflammatory). In the present work, these new active oxylipins, were detected for the first time in Acacia cyanophylla seeds collected in Tunisia from 7 ecotypes, using LC-MS/MS technology. The main PhytoP found was ent-9-L1-PhytoP, ranged from 3.30 ng/g (N-OB ecotype) to 19.14 ng/g (B-ZO ecotype). Three PhytoFs were detected with significantly higher values than PhytoPs. Multivariate analyses indicated a significant differentiation between compounds attributed to variation in climatic factors. This first complete PhytoP and PhytoF profile shows that Acacia cyanophylla Lindl. seeds could be as a new source of bioactive compounds for therapeutic and pharmaceutical applications.http://www.sciencedirect.com/science/article/pii/S2772753X2200065XAcacia cyanophylla Lindl. seedsPhytoprostanesPhytofuransMicro-LC-MS/MSClimatic conditions |
| spellingShingle | Marwa Mersni Bingqing Zhou Guillaume Reversat Islem Yangui Mohamed Larbi Khouja Alexandre Guy Camille Oger Jean-Marie Galano Thierry Durand Chokri Messaoud Claire Vigor Identification and quantification of phytoprostanes and phytofurans in Acacia cyanophylla Lindl. seeds Food Chemistry Advances Acacia cyanophylla Lindl. seeds Phytoprostanes Phytofurans Micro-LC-MS/MS Climatic conditions |
| title | Identification and quantification of phytoprostanes and phytofurans in Acacia cyanophylla Lindl. seeds |
| title_full | Identification and quantification of phytoprostanes and phytofurans in Acacia cyanophylla Lindl. seeds |
| title_fullStr | Identification and quantification of phytoprostanes and phytofurans in Acacia cyanophylla Lindl. seeds |
| title_full_unstemmed | Identification and quantification of phytoprostanes and phytofurans in Acacia cyanophylla Lindl. seeds |
| title_short | Identification and quantification of phytoprostanes and phytofurans in Acacia cyanophylla Lindl. seeds |
| title_sort | identification and quantification of phytoprostanes and phytofurans in acacia cyanophylla lindl seeds |
| topic | Acacia cyanophylla Lindl. seeds Phytoprostanes Phytofurans Micro-LC-MS/MS Climatic conditions |
| url | http://www.sciencedirect.com/science/article/pii/S2772753X2200065X |
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