Adverse effects following anti–COVID-19 vaccination with mRNA-based BNT162b2 are alleviated by altering the route of administration and correlate with baseline enrichment of T and NK cell genes

Ensuring high vaccination and even booster vaccination coverage is critical in preventing severe Coronavirus Disease 2019 (COVID-19). Among the various COVID-19 vaccines currently in use, the mRNA vaccines have shown remarkable effectiveness. However, systemic adverse events (AEs), such as postvacci...

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Bibliographic Details
Main Authors: Ayesa Syenina, Esther S. Gan, Justin Z. N. Toh, Ruklanthi de Alwis, Lowell Z. Lin, Christine Y. L. Tham, Jia Xin Yee, Yan Shan Leong, Huizhen Sam, Charlene Cheong, Yii Ean Teh, Ian L. E. Wee, Dorothy H. L. Ng, Kuan Rong Chan, Jean X. Y. Sim, Shirin Kalimuddin, Eugenia Z. Ong, Jenny G. Low, Eng Eong Ooi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-05-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9154185/?tool=EBI