SVM-based prediction of caspase substrate cleavage sites

<p>Abstract</p> <p>Background</p> <p>Caspases belong to a class of cysteine proteases which function as critical effectors in apoptosis and inflammation by cleaving substrates immediately after unique sites. Prediction of such cleavage sites will complement structural a...

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Bibliographic Details
Main Authors: Ranganathan Shoba, Tan Tin, Wee Lawrence JK
Format: Article
Language:English
Published: BMC 2006-12-01
Series:BMC Bioinformatics
Online Access:http://dx.doi.org/10.1186/1471-2105-7-S5-S14