SETDB2 interacts with BUBR1 to induce accurate chromosome segregation independently of its histone methyltransferase activity

SETDB2 is a H3K9 histone methyltransferase required for accurate chromosome segregation. Its H3K9 histone methyltransferase activity was reported to be associated with chromosomes during metaphase. Here, we confirm that SETDB2 is required for mitosis and accurate chromosome segregation. However, the...

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Bibliographic Details
Main Authors: Yanhong Tu, Haomiao Zhang, Jialin Xia, Yu Zhao, Ruifang Yang, Jing Feng, Xueyun Ma, Jing Li
Format: Article
Language:English
Published: Wiley 2024-03-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.13761