Insights from molecular docking and molecular dynamics on the potential of vitexin as an antagonist candidate against lipopolysaccharide (LPS) for microglial activation in neuroinflammation

Abstract Background Neuroinflammation has been identified to be the key player in most neurodegenerative diseases. If neuroinflammation is left to be unresolved, chronic neuroinflammation will be establish. Such situation is due to the overly-activated microglia which have the tendency to secrete an...

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Bibliographic Details
Main Authors: M. A. F. Yahaya, A. R. Abu Bakar, J. Stanslas, N. Nordin, M. Zainol, M. Z. Mehat
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Biotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12896-021-00697-4