A Novel Combination Therapy Approach Targeting STAT3 and Autophagy in Glioblastoma
The aggressive brain cancer glioblastoma (GBM) is notoriously resistant to radiotherapy and chemotherapy, which drives tumor recurrence and relapse. GBM cells are highly addicted to STAT3 (signal transducer and activator of transcription 3) and STAT3 inhibition blocks GBM-driven tumor growth. STAT3...
Main Authors: | Sujoy Bhattacharya, Lawrence M. Pfeffer, Edward Chaum |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2022-12-01
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Series: | Autophagy Reports |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/27694127.2022.2117340 |
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