Global state measures of the dentate gyrus gene expression system predict antidepressant-sensitive behaviors.

Global state measures of the dentate gyrus gene expression system predict antidepressant-sensitive behaviors.

Selective serotonin reuptake inhibitors (SSRIs) such as fluoxetine are the most common form of medication treatment for major depression. However, approximately 50% of depressed patients fail to achieve an effective treatment response. Understanding how gene expression systems respond to treatments...

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Bibliographic Details
Main Authors: Benjamin A Samuels, E David Leonardo, Alex Dranovsky, Amanda Williams, Erik Wong, Addie May I Nesbitt, Richard D McCurdy, Rene Hen, Mark Alter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3894967?pdf=render

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http://europepmc.org/articles/PMC3894967?pdf=render

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