Investigation of the Anticancer Effect of <i>α</i>-Aminophosphonates and Arylidine Derivatives of 3-Acetyl-1-aminoquinolin-2(<i>1H</i>)-one on the DMBA Model of Breast Cancer in Albino Rats with In Silico Prediction of Their Thymidylate Synthase Inhibitory Effect

Investigation of the Anticancer Effect of <i>α</i>-Aminophosphonates and Arylidine Derivatives of 3-Acetyl-1-aminoquinolin-2(<i>1H</i>)-one on the DMBA Model of Breast Cancer in Albino Rats with In Silico Prediction of Their Thymidylate Synthase Inhibitory Effect

Breast cancer is a major cause of death in women worldwide. In this study, 60 female rats were classified into 6 groups; negative control, <i>α</i>-aminophosphonates, arylidine derivatives of 3-acetyl-1-aminoquinolin-2(<i>1H</i>)-one, DMBA, DMBA & <i>α</i>-ami...

Full description

Bibliographic Details
Main Authors: Mohamed A. Nassan, Adil Aldhahrani, Hamada H. Amer, Ahmed Elhenawy, Ayman A. Swelum, Omar M. Ali, Yasser H. Zaki
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Molecules
Subjects:
<i>α</i>-aminophosphonates
3-acetyl-1-aminoquinolin-2(<i>1H</i>)-one
breast cancer
DMBA
thymidylate synthase
Online Access:https://www.mdpi.com/1420-3049/27/3/756

Internet

https://www.mdpi.com/1420-3049/27/3/756

Similar Items