Altered Synaptic Transmission and Excitability of Cerebellar Nuclear Neurons in a Mouse Model of Duchenne Muscular Dystrophy

Altered Synaptic Transmission and Excitability of Cerebellar Nuclear Neurons in a Mouse Model of Duchenne Muscular Dystrophy

Duchenne muscular dystrophy (DMD) is generally regarded as a muscle-wasting disease. However, human patients and animal models of DMD also frequently display non-progressive cognitive deficits and high comorbidity with neurodevelopmental disorders, suggesting impaired central processing. Previous st...

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Bibliographic Details
Main Authors: Tabita Kreko-Pierce, Jason R. Pugh
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Cellular Neuroscience
Subjects:
DMD
mdx
cerebellum
cerebellar nuclei
synaptic transmission
firing
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2022.926518/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2022.926518/full

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