Insulin receptor-mediated signaling regulates pluripotency markers and lineage differentiation

Objectives: Insulin receptor (IR)-mediated signaling is involved in the regulation of pluripotent stem cells; however, its direct effects on regulating the maintenance of pluripotency and lineage development are not fully understood. The main objective of this study is to understand the role of IR s...

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Bibliographic Details
Main Authors: Manoj K. Gupta, Dario F. De Jesus, Sevim Kahraman, Ivan A. Valdez, Farnaz Shamsi, Lian Yi, Adam C. Swensen, Yu-Hua Tseng, Wei-Jun Qian, Rohit N. Kulkarni
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877818306999