Combined analysis of the proteome and metabolome provides insight into microRNA-1174 function in Aedes aegypti mosquitoes

Combined analysis of the proteome and metabolome provides insight into microRNA-1174 function in Aedes aegypti mosquitoes

Abstract Background Pathogenic viruses can be transmitted by female Aedes aegypti (Ae. aegypti) mosquitoes during blood-meal acquisition from vertebrates. Silencing of mosquito- and midgut-specific microRNA (miRNA) 1174 (miR-1174) impairs blood intake and increases mortality. Determining the identit...

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Bibliographic Details
Main Authors: Yangrui Luo, Dun Liu, Yuanmei Wang, Fan Zhang, Yankun Xu, Qian Pu, Lu Zhao, Tianqi Wei, Ting Fan, Yuqi Lou, Shiping Liu
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Parasites & Vectors
Subjects:
Aedes aegypti
MicroRNA-1174
TMT proteomics
LC–MS/MS non-target metabolomics
Purine nucleoside phosphorylase
RNA interference
Online Access:https://doi.org/10.1186/s13071-023-05859-1

Internet

https://doi.org/10.1186/s13071-023-05859-1

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