Alisol B 23-Acetate Ameliorates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction by Inhibiting TLR4-NOX1/ROS Signaling Pathway in Caco-2 Cells

Alisol B 23-Acetate Ameliorates Lipopolysaccharide-Induced Intestinal Barrier Dysfunction by Inhibiting TLR4-NOX1/ROS Signaling Pathway in Caco-2 Cells

Alisol B 23-Acetate (AB23A) is a naturally occurring triterpenoid, which can be indicated in the rhizome of medicinal and dietary plants from Alisma species. Previous studies have demonstrated that AB23A could inhibit intestinal permeability by regulating tight junction (TJ)-related proteins. Even s...

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Bibliographic Details
Main Authors: Fan Xia, Yuxin Li, Lijun Deng, Ruxia Ren, Bingchen Ge, Ziqiong Liao, Shijian Xiang, Benjie Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Pharmacology
Subjects:
alisol B 23-acetate
intestinal barrier
tight junctions (TJs)
NADPH oxidase-1 (NOX-1)
toll-like receptor-4 (TLR4)
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.911196/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.911196/full

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