Newly Designed Poxviral Promoters to Improve Immunogenicity and Efficacy of MVA-NP Candidate Vaccines against Lethal Influenza Virus Infection in Mice

Newly Designed Poxviral Promoters to Improve Immunogenicity and Efficacy of MVA-NP Candidate Vaccines against Lethal Influenza Virus Infection in Mice

Influenza, a respiratory disease mainly caused by influenza A and B, viruses of the <i>Orthomyxoviridae</i>, is still a burden on our society’s health and economic system. Influenza A viruses (IAV) circulate in mammalian and avian populations, causing seasonal outbreaks with high numbers...

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Bibliographic Details
Main Authors: Martin C. Langenmayer, Anna-Theresa Luelf-Averhoff, Lisa Marr, Sylvia Jany, Astrid Freudenstein, Silvia Adam-Neumair, Alina Tscherne, Robert Fux, Juan J. Rojas, Andreas Blutke, Gerd Sutter, Asisa Volz
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Pathogens
Subjects:
influenza A virus
nucleoprotein
Modified Vaccinia virus Ankara
vaccine
synthetic VACV promoter
CD8+ T cell response
Online Access:https://www.mdpi.com/2076-0817/12/7/867

Internet

https://www.mdpi.com/2076-0817/12/7/867

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