Characterization of a novel positive allosteric modulator of the α1A-Adrenergic receptor

α1-Adrenergic Receptors (ARs) are G-protein Coupled Receptors (GPCRs) that regulate the sympathetic nervous system via the binding and activation of norepinephrine (NE) and epinephrine (Epi). α1-ARs control various aspects of neurotransmission, cognition, cardiovascular functions as well as other or...

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Bibliographic Details
Main Authors: Robert S. Papay, Jonathan D. Macdonald, Shaun R. Stauffer, Dianne M. Perez
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Current Research in Pharmacology and Drug Discovery
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590257122000621