Glycogen Synthase Kinase-3β Facilitates Cytokine Production in 12-O-Tetradecanoylphorbol-13-Acetate/Ionomycin-Activated Human CD4<sup>+</sup> T Lymphocytes

Glycogen Synthase Kinase-3β Facilitates Cytokine Production in 12-O-Tetradecanoylphorbol-13-Acetate/Ionomycin-Activated Human CD4<sup>+</sup> T Lymphocytes

Cytokines are the major immune regulators secreted from activated CD4<sup>+</sup> T lymphocytes that activate adaptive immunity to eradicate nonself cells, including pathogens, tumors, and allografts. The regulation of glycogen synthase kinase (GSK)-3β, a serine/threonine kinase, control...

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Bibliographic Details
Main Authors: Cheng-Chieh Tsai, Chin-Kun Tsai, Po-Chun Tseng, Chiou-Feng Lin, Chia-Ling Chen
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Cells
Subjects:
glycogen synthase kinase-3
cytokine
12-O-tetradecanoylphorbol-13-acetate/ionomycin
CD4<sup>+</sup> T lymphocyte
Online Access:https://www.mdpi.com/2073-4409/9/6/1424

Internet

https://www.mdpi.com/2073-4409/9/6/1424

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