<i>Ex vivo</i> venetoclax sensitivity testing predicts treatment response in acute myeloid leukemia

<i>Ex vivo</i> venetoclax sensitivity testing predicts treatment response in acute myeloid leukemia

The BCL-2 inhibitor venetoclax has revolutionized the treatment of acute myeloid leukemia (AML) in patients not benefiting from intensive chemotherapy. Nevertheless, treatment failure remains a challenge, and predictive markers are needed, particularly for relapsed or refractory AML. Ex vivo drug s...

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Bibliographic Details
Main Authors: Heikki Kuusanmäki, Sari Kytölä, Ida Vänttinen, Tanja Ruokoranta, Amanda Ranta, Jani Huuhtanen, Minna Suvela, Alun Parsons, Annasofia Holopainen, Anu Partanen, Milla E.L. Kuusisto, Sirpa Koskela, Riikka Räty, Maija Itälä-Remes, Imre Västrik, Olli Dufva, Sanna Siitonen, Kimmo Porkka, Krister Wennerberg, Caroline A. Heckman, Pia Ettala, Marja Pyörälä, Johanna Rimpiläinen, Timo Siitonen, Mika Kontro
Format: Article
Language:English
Published: Ferrata Storti Foundation 2022-12-01
Series:Haematologica
Online Access:https://haematologica.org/article/view/10906

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https://haematologica.org/article/view/10906

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