Human salivary protein-derived peptides specific-salivary SIgA antibodies enhanced by nasal double DNA adjuvant in mice play an essential role in preventing Porphyromonas gingivalis colonization: an in-vitro study

Abstract Background We previously showed that fimbriae-bore from Poryphyromonas gingivalis (Pg), one of the putative periodontopathogenic bacteria specifically bound to a peptide domain (stat23, prp21) shared on statherin or acidic proline-rich protein 1 (PRP1) molecule of human salivary proteins (H...

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Bibliographic Details
Main Authors: Kayo Koyanagi, Kosuke Kataoka, Hideki Yoshimatsu, Kohtaro Fujihashi, Tatsuro Miyake
Format: Article
Language:English
Published: BMC 2023-02-01
Series:BMC Oral Health
Subjects:
Online Access:https://doi.org/10.1186/s12903-023-02821-6