Age-related Changes in DNA Methylation Status of hTERT Gene Promoter of Oral Epithelial Cells

The purpose of this study was to investigate the effect of aging on the DNA methylation status of two genes involved in tumorigenesis (telomerase gene hTERT and DNA repair gene- MLH1) and one in metabolism (methylenetetrahydrofolate reductase gene- MTHFR) in oral epithelial cells. DNA methylation an...

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Bibliographic Details
Main Authors: Stephane Flaviane de Oliveira Bezerra, Ludimila de Araújo Costa, Priscylla Alves Nascimento de Freitas, Naila Francis Paulo de Oliveira
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2015-02-01
Series:Brazilian Archives of Biology and Technology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132015000100082&lng=en&tlng=en