Limited factor VIIa surface localization requirement of the factor VIIa–induced overall thrombin generation in platelet‐rich hemophilia A plasma

Abstract Background Thrombin generation assay (TGA) and thrombelastography (TEG) are increasingly employed, global, in vitro methods for assessment of the procoagulant potential of plasma/blood and possibly ideally suited tools to monitor, for example, therapy with recombinant factor VIIa (FVIIa). I...

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Bibliographic Details
Main Authors: Egon Persson, Mette Winther
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:Research and Practice in Thrombosis and Haemostasis
Subjects:
Online Access:https://doi.org/10.1002/rth2.12236