Cell Receptor and Cofactor Interactions of the Contact Activation System and Factor XI

The contact activation system (CAS) or contact pathway is central to the crosstalk between coagulation and inflammation and contributes to diverse disorders affecting the cardiovascular system. CAS initiation contributes to thrombosis but is not required for hemostasis and can trigger plasma coagula...

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Bibliographic Details
Main Authors: Monika Pathak, Bubacarr Gibril Kaira, Alexandre Slater, Jonas Emsley
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Medicine
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fmed.2018.00066/full