Oncometabolite 2-hydroxyglutarate regulates anti-tumor immunity

Oncometabolite 2-hydroxyglutarate regulates anti-tumor immunity

''Oncometabolite'' 2-hydroxyglutarate (2-HG) is an aberrant metabolite found in tumor cells, exerting a pivotal influence on tumor progression. Recent studies have unveiled its impact on the proliferation, activation, and differentiation of anti-tumor T cells. Moreover, 2-HG regu...

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Bibliographic Details
Main Authors: Mengyuan Cai, Jianyi Zhao, Qiang Ding, Jifu Wei
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Heliyon
Subjects:
2-Hydroxyglutarate
Isocitrate dehydrogenase
Tumor immune microenvironment
Oncometabolite
Therapeutic target
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024004857

Internet

http://www.sciencedirect.com/science/article/pii/S2405844024004857

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