Mechanism of inhibiting acetyl CoA carboxylase 2 to improve cardiac dysfunction in septic mice

Mechanism of inhibiting acetyl CoA carboxylase 2 to improve cardiac dysfunction in septic mice

Objective To observe the ameliorative effect of inhibiting acetyl-CoA carboxylase 2(ACC2) on cardiac dysfunction in septic mice and investigate its underlying mechanism. Methods Mouse model of sepsis was established by cecal ligation and perforation.A total of 24 male C57BL/6 mice (aged 8 weeks, wei...

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Bibliographic Details
Main Authors: DU Yunxia, SHE Han, WU Yinyu
Format: Article
Language:zho
Published: Editorial Office of Journal of Army Medical University 2024-12-01
Series:陆军军医大学学报
Subjects:
sepsis
cardiomyocytes
acetyl-coa carboxylase 2
calcium sensitivity
malonyl coa
Online Access:https://aammt.tmmu.edu.cn/html/202406038.htm

Internet

https://aammt.tmmu.edu.cn/html/202406038.htm

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