Apatinib Suppresses Proliferation and Induced Apoptosis of Human Breast Cancer Cell Line MDA-MB-231 Through Glycolytic Inhibition

Apatinib Suppresses Proliferation and Induced Apoptosis of Human Breast Cancer Cell Line MDA-MB-231 Through Glycolytic Inhibition

Objective To investigate the antitumor effect of apatinib on breast cancer cells in vitro and its mechanism. Methods CCK-8 assay was used to detect the inhibitory effect of apatinib on the proliferation of breast cancer cell line MDA-MB-231. Annexin V-FITC/PI apoptosis detection kit was used to dete...

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Bibliographic Details
Main Authors: ZHANG Huazhi, LI Xiaoshuang, GUO Xiaoye, ZHAO Mingchi
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2019-05-01
Series:Zhongliu Fangzhi Yanjiu
Subjects:
apatinib
breast cancer
apoptosis
aerobic glycolysis
Online Access:http://html.rhhz.net/ZLFZYJ/html/8578.2019.18.1422.htm

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http://html.rhhz.net/ZLFZYJ/html/8578.2019.18.1422.htm

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