Knockout of STE20-type kinase TAOK3 does not attenuate diet-induced NAFLD development in mice

Knockout of STE20-type kinase TAOK3 does not attenuate diet-induced NAFLD development in mice

Abstract Objective Non-alcoholic fatty liver disease (NAFLD), the primary hepatic consequence of obesity, is affecting about 25% of the global adult population. The aim of this study was to examine the in vivo role of STE20-type protein kinase TAOK3, which has been previously reported to regulate he...

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Bibliographic Details
Main Authors: Ying Xia, Emma Andersson, Mara Caputo, Emmelie Cansby, Francesca Sedda, Ferran Font-Gironès, Johan Ruud, Yeshwant Kurhe, Bengt Hallberg, Hanns-Ulrich Marschall, Ingrid Wernstedt Asterholm, Stefano Romeo, Matthias Blüher, Margit Mahlapuu
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Molecular Medicine
Subjects:
TAOK3
Non-alcoholic fatty liver disease
Non-alcoholic steatohepatitis
Systemic glucose and insulin homeostasis
Genetic compensation
Online Access:https://doi.org/10.1186/s10020-023-00738-y

Internet

https://doi.org/10.1186/s10020-023-00738-y

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